After completing this case the reader should be able to:

• Differentiate between indications for operative and cell-based non-operative management of osteoarthritis.
• Summarize proven and unproven data on cell-based therapeutics.
• Review the role of cell-based therapeutics to manage avascular necrosis of the femoral head.

Directed to primary care physicians including family practitioners and internists.

In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The Cleveland Clinic Foundation Center for Continuing Education designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

ABA MOC: This activity contributes to the CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in Anesthesiology™ (MOCA®) program, known as MOCA 2.0®. Please consult the ABA website, www.theABA.org, for a list of all MOCA 2.0 requirements.

Maintenance of Certification in Anesthesiology™ program and MOCA® are registered trademarks of The American Board of Anesthesiology®. MOCA 2.0® is a trademark of The American Board of Anesthesiology®. 

Your credit will be reported to the ABA within 30 days of claiming credit. 

ABIM MOC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.75 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Your credit will be reported to the ABIM within 30 days of claiming credit. 

ABO MOC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to satisfy the Lifelong Learning, Self-Assessment, Improvement in Medical Practice and/or Patient Safety requirements for the American Board of Ophthalmology’s Maintenance of Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting MOC credit.

Your credit will be reported to the ABO within 30 days of claiming credit. 

ABOHNS CC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn their required annual part II self-assessment credit in the American Board Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to satisfy the Lifelong Learning, Self-Assessment, Improvement in Medical Practice and/or Patient Safety requirements for the American Board of Ophthalmology’s Maintenance of Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting MOC credit.

Your credit will be reported to the ABO within 30 days of claiming credit.

ABPath MOC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 01.0 Lifelong Learning (Part II) / Self-Assessment Module (SAM) credits in the American Board of Pathology’s Maintenance of Certification Program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting MOC credit.
Your credit will be reported to the ABPath within 60 days of claiming credit after the course.

ABP MOC: Successful completion of this CME activity, which includes participation in the activity and individual assessment of and feedback to the learner, enables the learner to earn up to 0.75 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit. 

Your credit will be reported to the ABP within 30 days of claiming credit. 

ABS MOC: This activity qualifies for 0.75 self-assessment credits toward Part 2 of the American Board of Surgery (ABS) Maintenance of Certification (MOC) Program.

Please Note: It is the participant’s responsibility to self-report their participation to the American Board of Surgery, per board policy.

Activity Director

Anthony Fernandez, MD, PhD
Director, Medical and Inpatient Dermatology
W.D. Steck Chair of Clinical Dermatology
Medical Co-Director, Center for Continuing Education
Cleveland Clinic
Cleveland, OH

Faculty

Ahmed Emara, MD
Orthopaedic & Rheumatologic Institute 
Cleveland, OH

Nicolas S. Piuzzi, MD
Adult Joint Recontructive Surgery Associate Staff
Adult Joint Recontructive Surgery Research Director
Orthopaedic & Rheumatologic Institute 
Cleveland, OH

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.