Webcast CME

A Thread To Pull: Unraveling the Complexities of Myeloid Malignancies Webcast

Release date: January 16, 2023
Expiration date: January 16, 2025

Estimated Time of Completion: 3 hours

Description

A Thread To Pull: Unraveling the Complexities of Myeloid Malignancies Webcast provides an in-depth and up-to-date review of research related to biology, prognosis, natural history, and therapeutic management of patients with myeloid malignancies including PNH, MDS, AML, MPN and related myeloid malignancies. The overall goal of the education is to bring together leaders in disease research and clinical practice to explore solutions to improving the care of these patient populations.

Learning Objectives

  • Describe how the identification of clonal hematopoiesis can improve the assessment and management of patients with hematologic disorder of uncertain behavior. 
  • Critically review the evidence on treating patients with paroxysmal nocturnal hemoglobinuria and describe the implications for clinical practice.
  • Critically review the treatment strategies for MDS and the overlap between VEXAS syndrome and MDS.
  • Detail the safety and efficacy profiles of targeted and combination therapies for AML, their specific treatment indications, and toxicity and response assessment in daily clinical practice. 
  • Critically appraise the indications, efficacy, and adverse events for the expanding treatment options for patients with myeloproliferative neoplasms. 
  • List the recent management strategies for optimizing patient selection and improving outcomes in allogenic stem cell transplantation for patients with MDS and AML.

Target Audience

The webcast designed for an international audience including medical oncologists, hematologists, clinical and translational researchers, and other physicians, nurses, advanced practice nurses, physician assistants and allied health care professionals treating patients with MDS, AML and myeloid malignancies.

Accreditation

In support of improving patient care, this activity has been planned and implemented by Cleveland Clinic Center for Continuing Education and Aplastic Anemia and MDS International Foundation, Inc.  Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 

Credit Designation

American Medical Association (AMA) 
Cleveland Clinic Center for Continuing Education designates this enduring activity for a maximum of 3.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 
Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit. 

American Nurses Credentialing Center (ANCC) 
Cleveland Clinic Center for Continuing Education designates this enduring activity for a maximum of 3.0 ANCC contact hours. 

American Academy of PAs (AAPA) 
Cleveland Clinic Center for Continuing Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 3.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.

Certificate of Participation

A certificate of participation will be provided to other health care professionals for requesting credits in accordance with their professional boards and/or associations.

Activity Director and Faculty

Activity Director

Sudipto Mukherjee, MD, PhD, MPH
Cleveland Clinic
Cleveland, OH

Faculty

Rodrigo T. Calado, MD, PhD
Hospital das Clínicas de Ribeirão Preto
São Paulo, Brazil

Gabriela S. Hobbs, MD
Massachusetts General Hospital
Boston, MA

Bhumika J. Patel, MD
Prisma Health, University Medical Group
University of South Carolina School of Medicine Greenville
Greenville, SC

Guillermo Sanz, MD, PhD
Health Research Institute La Fe
Valencia, Spain

Craig S. Sauter, MD
Cleveland Clinic
Cleveland, OH

Roland B. Walter, MD, PhD, MS
Fred Hutchinson Cancer Center
Seattle, WA

Additional Planners/Reviewers

Deb Kangisser, PA-C

Cindy Willis, DNP

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Disclosures

In accordance with the Standards for Integrity and Independence issued by the Accreditation Council for Continuing Medical Education (ACCME), Cleveland Clinic Center for Continuing Education mitigates all relevant conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they may have a relationship, which in the context of their presentation(s), could be perceived as a potential conflict of interest:

Gabriela Hobbs, MD
Constellation, Incyte
 Advisor or review panel participant
Research: PI
Abbvie Pharmaceuticals
 Advisor or review panel participant
Bristol-Myers Squibb Co., Keros, Novartis, Pfizer, Pharmaxis
 Advisor or review panel participant

Sudipto Mukherjee, MBBS, PhD, MPH
Bristol-Myers Squibb Co.
 Advisor or review panel participant
Other activities from which remuneration is received or expected: Honoraria
Celgene Corporation
 Consulting
Advisor or review panel participant
Other activities from which remuneration is received or expected: Research Funding - non-therapeutic investigator trials. Formerly Celgene (now BMS)
Eusa Pharma
 Consulting
Advisor or review panel participant
Teaching and Speaking
Novartis
 Consulting
Advisor or review panel participant
McGraw Hill
 Other activities from which remuneration is received or expected: Honoraria - Editor of Hematology Oncology Board Review (ongoing)
Aplastic Anemia and MDS International Foundation
 Other activities from which remuneration is received or expected: Honorarium - Activity Director of ASH Friday Satellite Symposium annually
Jazz Pharmaceuticals
 Research: Principal Investigator for Investigator Initiated Trials (The institution gets the funding)
Abbvie Pharmaceuticals , Blueprint Medicines
 Advisor or review panel participant

Bhumika Patel, MD
Alexion, Apellis Pharmaceuticals
 Consulting
Teaching and Speaking
Novartis Pharmaceuticals
 Consulting

Guillermo Sanz, MD
Abbvie Pharmaceuticals, Helsinn , La Hoffman Roche Ltd., Takeda Pharmaceutical Ltd
 Advisor or review panel participant
Celgene Corporation, Novartis Oncology
 Consulting
Janssen Pharmaceuticals, Inc.
 Teaching and Speaking

Craig Sauter, MD
CRISPR (CRSP), CSL Behring, Gamida Cell, Karyopharm Therapeutics Inc., Kite Pharma Inc., Ono Pharmaceuticals, Syncopation Life Sciences
 Consulting
BMS, Genzyme/Sanofi, Precision Biosciences
 Research: PI

Roland B Walter, MD
Agios Pharmaceuticals, Kite Pharma Inc.
 Consulting
Principal or Co-Investigator of funded research
Aptevo, Arog, Kura
 Research: Local investigator on company-sponsored trial
Celgene Corporation, Janssen
 Consulting
Research / Independent Contractor
Principal or Co-Investigator of funded research
ImmunoGen, Inc
 Research / Independent Contractor
Principal or Co-Investigator of funded research
Jazz Pharmaceuticals, MacroGenics, Selvita
 Principal or Co-Investigator of funded research
Pfizer
 Consulting
Research / Independent Contractor
Amphivena
 Ownership interest (stock, stock options in a publicly owned company)
Astellas Pharma US, Inc., BMS, Genentech, GSK
 Consulting

The following faculty have indicated they have no relationship which, in the context of their presentation(s), could be perceived as a potential conflict of interest:

Rodrigo T Calado, MD
Debra Kangisser, PA-C
Cynthia Willis, DNP

 

Acknowledgement

The Cleveland Clinic Center for Continuing Education and the Aplastic Anemia and MDS International Foundation, Inc. acknowledges educational grants for partial support of this Internet Enduring activity from:

BioCryst US Sales Co., LLC
Geron Corporation
Gilead Sciences, Inc.
Incyte Corporation
Karyopharm Therapeutics
Taiho Oncology, Inc.

 

This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and Aplastic Anemia and MDS International Foundation, Inc.