Free Online CME

Cleveland Clinic Tall Rounds®: Caring for Your Patients with ATTR

Transthyretin Cardiac Amyloidosis: Diagnosis, Treatment, and Management

Release date: 3/31/25
Expiration date: 3/30/26

Estimated Time of Completion: 1 hour

Description

Early diagnosis and intervention for transthyretin amyloidosis (ATTR) is critical, yet does not occur, typically as a consequence of the rarity and heterogeneity of the disease and limited awareness on the part of clinicians. Therapeutic options are limited, but there are new and emerging agents and emerging indications with which clinicians may not be familiar. Access to specialized care centers is limited for many patients, leading to suboptimal management and disease monitoring. This education fills a significant need for healthcare team education to ensure all patients benefit from best-practices in recognizing, diagnosing, and managing amyloidosis. Learn More about the Cleveland Clinic Amyloidosis Center

Learning Objectives

  • Identify the signs, symptoms, and screening tests used to diagnose transthyretin amyloidosis cardiomyopathy (ATTR-CM).
  • Select the optimal treatment for a patient with a confirmed diagnosis of ATTR-CM.
  • Develop a management and monitoring plan for a patient with ATTR-CM based on patient’s characteristics, biomarkers, and imaging studies.

Target Audience

The online series is designed for physicians, nurses, physician assistants, and other members of the clinical team who care for patients with ATTR. Other professions like pharmacists and genetic counselors who focus on neurology and/or cardiology may also be interested.

Accreditation

In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians / American Medical Association (AMA)
Cleveland Clinic Center for Continuing Education designates this internet enduring activity for a maximum of 1.5 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Certificate of Participation
A certificate of participation will be provided to other health care professionals for requesting credits in accordance with their professional boards and/or associations.

Activity Director and Faculty

Activity Director

Eric Roselli, MD

Planning Committee

Deb Kangisser, PA
Jeanna Sigmund, MSN

Faculty

Mazen Hanna, MD

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic. In no event will The Cleveland Clinic be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Disclosures

In accordance with the Standards for Integrity and Independence issued by the Accreditation Council for Continuing Medical Education (ACCME), the Cleveland Clinic Center for Continuing Education mitigates all relevant conflicts of interest to ensure CME activities are free of commercial bias. All relevant financial relationships have been mitigated.

The following faculty have indicated that they may have a relationship, which in the context of their presentation(s), could be perceived as a potential conflict of interest:

Eric Roselli, MD

Artivion, Edwards Lifesciences, LivaNova, PLC

Consulting
Teaching and Speaking

Abbott, Cook Medical, Terumo

Teaching and Speaking

Cryolife, Inc., Medtronic, W.L. Gore & Associates

Consulting
Mazen Hanna, MD

Akcea Therapeutics, Inc., Alexion, Alnylam, Eidos Therapeutics, Pfizer

Advisor or review panel participant

Acknowledgment

The Cleveland Clinic Center for Continuing Education acknowledges educational grants for partial support of this activity from:

Alexion Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

AstraZeneca Pharmaceuticals

This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education, The France Foundation, and Cleveland Clinic’s Heart, Vascular and Thoracic Institute.

For further information about this activity, contact Katie Breznai at [email protected]