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Technical Requirements

 

Volume 77, Supplement 2

Preventing and Treating Acute Gout Attacks Across the Clinical Spectrum: A Roundtable Discussion

First Step: Review Information Below to Begin Activity

Release Date: June 1, 2010
Expiration Date: June 1, 2012

Estimated Time of Completion: 2 hours

Description

This single-article journal supplement is the edited transcript of a roundtable discussion convened at Cleveland Clinic by the Cleveland Clinic Journal of Medicine on February 6, 2010. The roundtable consisted of four veteran rheumatologists with special interest in gout and a hospitalist/infectious disease specialist. Their objective was to generate a practical dialogue on evidence-based approaches to the acute gout attack in various clinical settings for generalist physicians as well as rheumatologists. The topics addressed, often in a case-based context, included the treatment implications of a presumptive diagnosis of gout, appropriate therapies and dosing for acute gout attacks, the influence of comorbidities on therapy choices, preventing gout flares during long-term urate-lowering therapy, and management of acute gout in the perioperative setting. This supplement captures the essence of the discussion and its key teaching points, enhanced with tables developed by the faculty after the discussion.

Objectives

Upon completing this activity, participants will be able to:

  1. Describe when proceeding with a presumptive diagnosis of gout is reasonable and when diagnostic confirmation with synovial fluid analysis is mandatory.
  2. Name and discuss the treatment options for acute gout in outpatient and inpatient settings.
  3. Identify comorbidities that influence the choice of therapy for acute gout flares and explain how each comorbidity affects treatment recommendations.
  4. Recognize the need to use and maintain prophylactic anti-inflammatory therapy when initiating urate-lowering therapy.

Target Audience

Internists, family and general practitioners, rheumatologists, hospitalists, emergency physicians, and other physicians who manage patients with or at risk for acute gout.

Accreditation

The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this educational activity for a maximum of 2.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association Council on Continuing Medical Education for Category 2 credit.

Activity Director and Supplement Editor

Brian F. Mandell, MD, PhD
Professor and Chairman of Medicine, Education Institute,
and Department of Rheumatic and Immunologic Disease,
Center for Vasculitis Care and Research,
Cleveland Clinic,
Cleveland, OH





Faculty

N. Lawrence Edwards, MD
Professor of Medicine,
Division of Rheumatology and Clinical Immunology,
University of Florida,
Gainesville, FL
James C. Pile, MD
Assistant Professor of Medicine,
Divisions of Hospital Medicine and Infectious Diseases,
Case Western Reserve University/MetroHealth Medical Center,
Cleveland, OH
   
Peter A. Simkin, MD
Emeritus Professor of Medicine,
Division of Rheumatology,
University of Washington School of Medicine,
Seattle, WA
John S. Sundy, MD, PhD
Associate Professor of Medicine,
Division of Rheumatology and Immunology and
Division of Pulmonary and Critical Care Medicine,
Duke University Medical Center,
Durham, NC

Disclosures

In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they have a relationship which, in the context of their contributions, could be perceived as a potential conflict of interest:

Brian F. Mandell, MD, PhD (Activity Director)
  Consulting (one-time consultation):

URL Pharma

  Consulting and teaching/speaking (in a funded CME program): Takeda Pharmaceuticals
 
N. Lawrence Edwards, MD
  Consulting: Takeda Pharmaceuticals and Savient Pharmaceuticals
James C. Pile, MD
  Membership on advisory committee/review panel: Pfizer
     
Peter A. Simkin, MD
  Membership on advisory committees: Novartis and URL Pharma
     
John S. Sundy, MD, PhD
  Consulting: Alnara Pharmaceuticals, Anadys Pharmaceuticals, Ardea Biosciences, Regeneron Pharmaceuticals, and Savient Pharmaceuticals
  Contracted research (through Duke University Medical Center): Ardea Biosciences, Genentech, Neopharm, Regeneron, and Savient
  Membership on advisory committee/review panel: Ardea Biosciences
  Teaching/speaking: Takeda Pharmaceuticals

All other planners, CME staff, and content reviewers reported that they have no relevant financial relationships to disclose.

Acknowledgment

The Cleveland Clinic Foundation Center for Continuing Education acknowledges an educational grant for support of this activity from Mutual Pharmaceutical Company, Inc. (URL Pharma, Inc.), whose products include a brand-name version of colchicine, which is among the therapies discussed in this supplement.

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This CME activity was produced by the Cleveland Clinic Journal of Medicine and the Cleveland Clinic Center for Continuing Education.

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