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Agenda

Epileptology: Comprehensive Review and Practical Exercises (Oct. 1 - 3)
Friday, October 1  |  Saturday, October 2  |  Sunday, October 3  

Epilepsy Surgery: Invasive Evaluation (Oct. 3 - 6)
Sunday, October 3  |  Monday, October 4  |  Tuesday, October 5  |  Wednesday, October 6

Epileptology: Comprehensive Review and Practical Exercises
  Friday, October 1
7:45 am Welcome, Course Introduction
8:00 am Lecture: Mechanisms of Epilepsy - Imad Najm
8:45 am Lecture: Genetics of Epilepsy – Jocelyn Bautista
9:30 am Lecture: EEG Diagnosis of Epilepsy – Dileep Nair
10:15 am Break
10:30 am Lecture: Pediatric Epilepsy Syndromes – Deepak Lachhwani
11:15 am Lecture: Adult Epilepsy Syndromes – Stephen Hantus
12:00 pm Lunch
1:30 pm Parallel Workshops:
  1. Pediatric EEG
    Moderators: Ingrid Tuxhorn/Ajay Gupta
    Panel: Deepak Lachhwani, Prakash Kotagal

  2. Adult EEG
    Moderators: Andray Stojic/ Paul Shkurovich
    Panel: Stephan Schuele, Juan Bulacio

3:00 pm Break
3:30 - 5:00 pm Parallel Workshops:
  1. Pediatric Seizure Semiology – Moderators: Prakash Kotagal/ Deepak                                     Lachhwani
    Panel: Ingrid Tuxhorn, Juan Bulacio

  2. Adult Seizure Semiology -  Andreas Alexopoulos/ Juan Bulacio
    Panel: Stephan Schuele, Paul Shkurovich

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  Saturday, October 2
8:00 am Lecture: Medical Management of Adult Epilepsy – Norman So
9:00 am Lecture: Medical Management of Pediatric Epilepsy – Prakash Kotagal
10:00 am Break
10:15 am Lecture: Selection of Adult Epilepsy Surgery Candidates – Lara Jehi
11:00 am Lecture: Selection of Pediatric Epilepsy Surgery Candidates – Ajay Gupta
12:00 pm Lunch
1:30 pm Lecture: Surgical Management of Epilepsy – William Bingaman
2:00 pm Lecture: Invasive Monitoring - Indications and Techniques - Jorge Gonzalez-Martinez
2:30 pm Break
3:00 - 4:30 pm Parallel Workshops:
  1. Pediatric Epilepsy Surgery Case Discussions
    Moderators: Elaine Wyllie / William Bingaman
    Panel: Ajay Gupta, Prakash Kotagal

  2. Adult Epilepsy Surgery Case Discussions -
    Moderators: Imad Najm/Jorge Gonzalez-Martinez
    Panel: Lara Jehi, Stephen Hantus

  Sunday, October 3
8:00 am Lecture: Neuroimaging in Epilepsy – Paul Ruggieri
8:45 am Lecture: Epilepsy in Women – Nancy Foldvary
9:30 am Break
9:45 am Lecture: Psychiatric Co-morbidities Associated with Epilepsy – George Tesar
10:30 am Lecture: Status Epilepticus and SUDEP – Andreas Alexopoulos
11:30 am Lunch
1:00 pm Parallel Workshops:
  1. Medical Management of Adult Epilepsy
    Moderators: Norman So / Chetan Malpe          
    Panel: Nancy Foldvary, Silvia Neme, Aleksandar Ristic

  2. Medical Management of Pediatric Epilepsy
    Moderator: Prakash Kotagal
    Guest Moderator:
    Panel: Deepak Lachhwani, Juan Bulacio, Ingrid Tuxhorn

2:30 pm Break
3:00 pm Parallel Workshops:
  1. Management of Psychiatric Comorbidities
    Moderators:  George Tesar/    Tatiana Falcone
    Panel: Danielle Humbel, Andreas Alexopoulos

  2. Management of Epilepsy in Women
    Moderator: Nancy Foldvary
    Panel: Stephan Schuele, Silvia Neme

  Sunday, October 3 - Ethics of Invasive Brain Testing: Limits and Responsibilities (Click here to view PDF)
8:00 - 5:00 pm Organizers – Paul Ford, PhD

Clinicians and researchers are faced with ethically intricate challenges with the continued advancement of invasive technologies
for monitoring and testing brain functioning. These technologies allow us to localize seizure foci, map functional areas, and explore
therapeutic stimulation with applications to epilepsy, tumors, neurodegenerative diseases, and psychiatric disorders. These tests are
performed on patients who become unusually vulnerable to power differences and manipulation. We have great potential to manipulate a
person’s cognition, mood, or mind through these processes. We need to have clear reasons and justifications for choosing:

  • Which technologies we use
  • Which patients we use them on
  • How we use them on patients
  • What research questions we tackle
  • How we tackle those research projects

Threaded through these challenges are deeply held value convictions about justice, professionalism, and responsibility.

  Sunday, October 3 - Hands-On Surgical Workshop for Neurosurgeons
12:00 - 5:00 pm Workshop Organizers – William Bingaman, MD and Jorge Gonzalez-Martinez, MD, PhD

This highly successful half-day hands-on dissection workshop demonstrates some commonly used epilepsy surgery techniques that include various approaches to temporal lobe resection and hemispherectomy/disconnection methods. Cleveland Clinic Epilepsy Surgery faculty and worldrenowned neurosurgeons in the field of epilepsy surgery will discuss their choices for surgical techniques, and demonstrate their surgical approaches in a highly interactive and hands-on workshop.

Epilepsy Surgery: Invasive Evaluation
  Monday, October 4
7:45 am Welcome and Introductory Remarks
Session I Clinical Successes: What Are We Doing Right (Patterns/Location/Pathology)?
8:00 am Introduction – Dileep Nair (Moderator)
8:10 am Stereo-Electroencephalography (SEEG) - Philippe Kahane
8:35 am Subdural Grid Electrodes (SDG) - Juan Bulacio
9:00 am Intraoperative Electrocorticography (ECoG) - Ajay Gupta
Session II Clinical Failures: What Are We Missing (Patterns/Location/Pathology)?
9:25 am Introduction – Jorge Gonzalez-Martinez (Moderator)
9:35 am Stereo-Electroencephalography (SEEG) - Laura Tassi
10:00 am Subdural Grid Electrodes (SDG) - Lara Jehi
10:25 am Intraoperative-Electrocorticography (ECoG) - Andre Palmini
11:00 - 11:50 am The Third Dudley S. Dinner Distinguished Epileptologist's Lecture
Invasive Monitoring in Epilepsy: Past, Present and Future - Dennis Spencer, MD

See information on Dudley Dinner, MD    |   See information on Dennis Spencer, MD

11:50 am Lunch
Session III Fundamental Concepts: Applications/Limitations
1:00 pm Introduction – Americo Sakamoto (Moderator)
1:10 pm Dynamic Aspects of the “Epileptic Zones”: Current vs Dormant Epileptogenicity - Imad Najm
1:35 pm Penfield/Jasper Concept - Andre Palmini
4:00 pm Talairach/Bancaud Concept - Patrick Chauvel
2:25 pm Neuromodulation of the Epileptic Brain - Jorge Gonzalez-Martinez
14:50 Coffee Break
Session IV Roles of Various Techniques in the Indication and Choice of the Invasive Methods
3:20 pm Introduction – Fernando Cendes (Moderator)
3:30 pm Indications for Invasive Monitoring: Candidates and Goals - Norman So
3:50 pm Role of Scalp EEG – Nancy Foldvary
4:10 pm Role of Seizure Semiology – Walter Van Emdeboss
4:30 pm Role of Magnetic Resonance Imaging – Fernando Cendes
4:50 pm Role of PET Metabolic Imaging - Armin Mohamed
5:10 pm Role of Ictal SPECT – Greg Cascino
5:30 pm Role of Magnetoencephalography (MEG) - Andreas Alexopoulos
  Tuesday, October 5
  Parallel Session I
 
Electrical Markers of Dormant Epileptogenicity: The Issue of Late Postsurgical Recurrence
Parallel Session II
 
Invasive Indications in Temporal Lobe Epilepsies (Lesional/Non-lesional)

Parallel Session III
 
Cortical Connectivity Through Imaging and Electrophysiology

8:00 am Introduction – Andre Palmini (Moderator) Introduction – Norman So (Moderator) Introduction – Paul Ruggieri (Moderator)
8:10 am SEEG Markers - Lorella Minotti Lesional TLE: Pros and Con - Fernando Cendes Anatomic Measures - Jeremy Schmahmann
8:35 am Subdural Markers – Dileep Nair Non-lesional TLE - Americo Sakamoto MRI Measures - Steven Jones
9:00 am Intraoperative ECoG Markers - Eliseu Pagioli Temporal Plus - Lorella Minotti  MEG Measures - John Mosher
9:25 am Discussion Pseudo Temporal vs Pseudo Extratemporal - Andre Alexopoulos SEEG/Subdural - Jorge Gonzalez-Martinez
9:50-10:05 am Coffee Break
  Parallel Session IV
 
Electrophysiologic Surrogate Markers of Epileptogenicity
  Parallel Session V
 
Invasive Evaluation of Extratemporal Lobe Epilepsies (Lesional)
Parallel Session VI
 
Psychiatric / Nursing / Socioeconomic Issues Associated with an Invasive Evaluation
10:05 am Introduction - Richard Burgess (Moderator) 10:05 am Introduction - Prakash Kotagal (Moderator) Social Impact of Epilepsy on Society - Raquel Bialik
10:15 am Interictal Patterns- Intraop ECoG - Andre Palmini  10:15 am Frontal Lobe Epilepsy - Deepak Lachhwani / Americo Sakamoto Invasive Evaluation in Patients with Psychiatric Co-Morbidities - George Tesar
10:30 am Interictal/Ictal Patterns- Subdural Grids - Peter Widdess-Walsh 10:40 am Central Lobe Epilepsy - Jocelyn Bautista Invasive Evaluation in Children (Special Considerations) - Tatiana Falcone
10:45 am Interictal/Ictal Patterns- SEEG – Laura Tassi 11:05 am Parieto-occipital Lobe Epilepsy - Stephen Hantus Socioeconomics of Invasive Evaluation - Lara Jehi
11:00 am Fast Oscillations - Jean Gotman 11:30 am Mesial / Inter-hemispheric Epilepsy - Andrew Bleasel Nursing Issues Related to Invasive Evaluation - Diane Cleary
11:15 am DC Shift - Akio Ikeda 11:55 am Periventricular Nodular Heterotopia – Francois Dubeau Discussion
11:30 am Direct Stimulation Lorella Minotti      
11:45 am Evoked Cortical Responses - Dileep Nair      
12:00 pm Microelectrode Recordings - Greg Worrell      
12:15 pm Lunch Break
1:00 - 2:30 pm Case Discussions I Surgical Workshop I: The Invasive Approach to Temporal Lobe Epilepsies
Moderators: Philippe Kahane, Ameriko Sakamoto, Norman So
Panel Members: Deepak Lachhwani, Laura Tassi, Georgio LoRusson
The Invasive Approach to Temporal Lobe Epilepsies
Moderators:
Philippe Khane, Ameriko Sakamoto, Norman So

Panel Members:
Deepak Lachhwani, Laura Tassi, Eliseau Paglioli
1:00 pm Principles of SEEG: Indications, planning and implantation techniques – Giorgio Lo Russon
1:30 pm Depth electrodes: Indications and Techniques - William Bingaman
2:00 pm Foramen Ovale: Indications and Techniques - Carlos Carlotti
2:45 - 4:15 pm Case Discussions II Surgical Workshop II: Pitfalls, Controversies, and Management of Complications in Invasive Monitoring
Moderators: William Bingaman and Eliseu Paglioli
The Invasive Approach to Extratemporal Lobe Epilepsies 2:45 pm Intraoperative ECoGs - Eliseu Paglioli
3:15 pm Subdural Grids and Strips - Michael Sather
3:45 pm SEEG - Stephan Chabardes
4:30 - 6:30 pm Round Table Discussion
The Invasive Evaluation of Nonlesional Epilepsies
Moderators: Dileep Nair and Andre Palmini
4:30 pm Penfield/Jasper Approach to Nonlesional Epilepsy -  Frederick Andermann
5:00 pm Talairach/Bancaud Approach to Nonlesional Epilepsy – Philippe Kahane
5:30 pm Panel Discussion - Frederick Andermann, Mar Carreno, Francios Dubeau, Philippe                                                Kahane, Americo Sakamoto
6:30 pm Adjourn
  Wednesday, October 6
  Parallel Session VII
 
Neurophysiologic Eloquent Cortex Mapping
  Parallel Session VIII
 
Invasive Evaluation in Pediatric Epilepsy
  Parallel Session IX
 
Alternative Noninvasive Techniques for Localization of Epileptogenicity
8:00 am Introduction - Riki Matsumoto and Dileep Nair (Moderator's) 8:00 am Introduction - Ajay Gupta and Helio Machado (Moderator's) 8:00 am Introduction - Richard Burgess and Jean Gotman (Moderator's)
8:10 am High Gamma Eloquent Cortex Mapping - Nathan Crone 8:05 am Invasive Indications in Children - Prakash Kotagal 8:10 am MRI Techniques - Chong Wong
8:35 am Cortical Stimulation Mapping - Dileep Nair 8:30 am When Can Invasives be Avoided in Children - Elaine Wyllie 8:30 am MEG - Rick Burgess
9:00 am Cortico-Cortical Evoked Potentials Functional Mapping - Riki Matsumoto 8:55 am Cortical Dysplasia - Michael Duchowny 8:50 am Receptor Imaging – PET- Csaba Juhasz
9:25 am Event Related Potentials Mapping - Akio Ikeda 9:20 am Tumors - Hans Holthausen 9:10 am EEG High Density Arrays - Mark Holmes
9:50 am Discussion 9:45 am Tuberous Sclerosis 9:30 am EEG-Triggerred fMRI - Jean Gotman
        9:50 am Discussion
10:10 am Coffee Break
  Case Discussions III
Pediatric Invasive Cases
Panel Members Michael Duchowny and Hans Holthausen
Case Discussions IV
Use of MEG / fMRI
Panel Members: John Mosher, Richard Burgess, Stephen Jones
10:30 - 12:00 pm Case #1 Epileptogenicity in Cortical Dysplasia - Prasanna Jayakar
Case #2 Tumors - Ingrid Tuxhorn
Case #3 Epileptogenicity in Tuberous Sclerosis - Ajay Gupta
Simultaneous Invasive and MEG recordings – Andreas Alexopoulos
Ictal fMRI and Invasive Recordings - Ajay Gupta
fMRI Speech lateralization - Stephen Jones
12:00 pm Adjourn
   
 
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Center for Continuing Education | 9500 Euclid Avenue, KK31, Cleveland, OH 44195
Cleveland Clinic Center for Continuing Education © 2001-2012. All Rights Reserved.
Center for Continuing Education | 9500 Euclid Avenue, KK31, Cleveland, OH 44195