Table 1. Characteristics of the Two Types of Heparin-Induced Thrombocytopenia
Characteristic | Type I | Type II |
---|---|---|
Frequency | 10 to 20% | |
Timing of onset | 2 to 3 days | 5 to 10 days |
Nadir platelet count | 100,000/µl | 10,000 to 20,000/µl |
Antibody mediated | No | Yes |
Thromboembolic sequelae | None | 30 to 80% |
Treatment | Observe Patient | Discontinue heparin by all routes, select other anticoagulation, adjunctive therapy |
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