Table 2. Pharmacokinetics of Methylphenidate Formulations
|
Drug
|
Cmax
(ng/mL) |
Tmax
(hrs) |
Half-life
(hrs) |
Duration
of action
(hrs) |
|
Ritalin®
|
4.2
|
0.3
- 4.4
|
1.5
- 2.5
|
3
- 4
|
|
Ritalin
SR®
|
4.56
|
1.3
- 8.2
|
4
|
6-8
|
|
Concerta™
|
3.7
|
6.8
|
3.5
|
Up
to 14
|
Cmax = maximum concentration;
Tmax = time to maximum concentration
Adapted from product labeling
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