Table 2. Interactions between Herbs and Cardiovascular Agents

Medication
Natural Medicine
Antiarrhymthics
Aloe Latex (possible loss of intestinal potassium leading to a decrease in serum potassium)
Antihypertensives Devil's Claw, European Mistletoe, Fish Oils, Ginger, Goldenseal, Hawthorne, Licorice, Stinging Nettle, Yohimbe

Calcium Channel Blockers

Dong Quai (synergistic effects), Ginger (increase calcium uptake by heart muscle), Grapefruit juice, St. John's Wort
Carvedilol (Coreg ®) Grapefruit juice
Cardiac Glycosides Alder Buckthorn (loss of serum potassium), Aloe Latex (possible loss of intestinal potassium leading to a decrease in serum potassium), Cascara (loss of serum potassium), Ephedra (dysrhythmias), European Buckthorn (loss of serum potassium), Licorice (potentiate actions)
Coronary Vasodilators Hawthorn (additive effects)
Digoxin (Lanoxin ®) Aloe (possible loss of intestinal potassium leading to a decrease in serum potassium), Digitalis, Ephedra, Guar Gum, Hawthorn (increased cardiac toxicity, Licorice (loss of serum potassium), Pectin, Psyllium (decreased absorption), Siberian Ginseng (increased digoxin levels), St. John's Wort
HGM-CoA Reductase Inhibitors Grapefruit juice
Potassium-depleting Diuretics Licorice (additive effects)
Thiazide Diuretics Ginko leaf extract

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