Table 1: Glucovance™ Dosing
|
Type
of Therapy
|
Initial
Dose
|
Dose
Adjustment
|
Maximum
Dose
|
|
First-line
therapy of Type 2 DM
|
1.25
mg/250 mg
once or twice daily with meals |
Increase
by 1.25 mg/250 mg every 2 weeks until treatment goals are achieved.
|
10
mg/2000 mg
|
|
Second-line
therapy of Type 2 DM
|
2.5
mg/500 mg or
5 mg/500 mg twice daily with meals |
Increase
by no more than 5 mg/500 mg every 1 to 2 weeks until treatment goals are
achieved.
|
20
mg/2000 mg
|
Adapted from: Glucovance™
package insert. Princeton, NJ: Bristol-Myers Squibb: 2000 July
DM = diabetes mellitus
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