| THURSDAY, NOVEMBER 1 |
| 7:00 am |
Registration, Continental Breakfast & Exhibits
MBNA Conference Center, 3rd Floor |
| 8:00 am |
Opening Remarks and Welcome Address
Brief Overview of Breath Analysis - Raed A. Dweik
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Exhaled Nitric Oxide: From Discovery, To Instrumentation, To Clinical Application
Chairs: Serpil C. Erzurum, Raed A. Dweik |
| 8:15 am |
NO from NOS - Dennis Stuehr |
| 8:45 am |
Sources of NO in Exhaled Breath -Benjamin Gaston |
| 9:00 am |
Technical and Regulatory Aspects of Exhaled NO Measurements - Phillip Silkoff |
| 9:30 am |
Clinical Applications of Exhaled NO - Raed A. Dweik |
| 9:45 am |
Refreshment Break, Exhibits, Posters |
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Selected Abstract Presentations (non-CME) |
| 10:00 am |
Lung Diffusion Capacity for Nitric Oxide and Carbon Monoxide: Methodological Issues and Reproducibility - Werner Steinhaeusser |
| 10:10 am |
Exhaled Nitric Oxide as Noninvasive Markers of Airway Inflammation from Work Exposures - Massimo Corradi |
| 10:20 am |
Changes in Concentrations of Carbon Monoxide and Nitric Oxide in Breath and Skin Gas during Smoking Cessation and Restart - Kazutoshi Nose |
| 10:30 am |
Nitric Oxide Breath Analysis with a Room Temperature Infrared Laser System - Joanne Shorter |
| 10:40 am |
A Fresh Approach to Exhaled Nitric Oxide Measurement using a Fast-Response, Low-Cost Electronic Indicator - Leigh Greenham |
| 10:50 am |
Novel Electrochemical Nitric Oxide Gas Sensor for Breath Analysis - Kerstin Wex |
| 11:00 am |
Panel Discussion
Moderator: Serpil C. Erzurum
Panel: Denis Stuehr, Benjamin Gaston, Phillip Silkoff, Raed Dweik |
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Mass Spectrometry and Benchtop Instrumentation
Chairs: David Smith |
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Overview and Technical Aspects of Mass Spectrometry Technologies |
| 11:30 am |
Introduction and Overview - Anton Aman |
| 12:00 pm |
Current Advances in SIFT-MS - Patrik Spanel |
| 12:15 pm |
Metabolites in Human Breath - Jörg Ingo Baumbach |
| 12:30 pm |
Lunch, Exhibits, Posters |
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Breath Analysis by Mass Spectrometry
Chair: Patrik Spanel |
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Selected Abstract Presentations (non-CME) |
| 1:30 pm |
The Combined use of Thermal Desorption and Selected Ion Flow Tube Mass Spectrometry for the Quantification of Volatile Compounds in Breath - Brian Ross |
| 1:45 pm |
Optimized Set-Up for On-Line Breath Analysis with PTR-MS - Jens Herbig |
| 2:00 pm |
Time Resolved Monitoring of VOC Concentration Profiles in Breath along the Expiratory Phase - Siegfried Praun |
| 2:15 pm |
Longitudinal Study to Observe Qualitative Variation in Male Breath over a Five Day Period, using 2-Dimensional Gas Chromatography and Time of Flight Mass Spectroscopy - Simon Stevens |
| 2:30 pm |
Analysis of Volatile Metabolites from Cultured Bacteria by Gas Chromatography/Atmospheric Pressure Chemical Ionization-Mass Spectrometry - Masako Ishimaru |
| 2:45 pm |
Identification of Specific Volatile Organic Compounds from Mycobacteria in Vitro - Mona Syhre |
| 3:00 pm |
Stress Responses during Parabolic Flight Maneuvers are Reflected by Changes In Expiratory Air - Alexander Chouker |
| 3:15 pm |
Refreshment Break, Exhibits, Posters |
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Poster Sessions: Technical Aspects of Mass Spectrometry Technologies |
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SIFT-MS Analyses of the Breath of Volunteers in Three Age Groups - Kseniya Dryahina |
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Expiratory Air Analyses by Online Mass Spectrometry: Co2 vs Isoprene Controlled Detection Of Alveolar Gas - Michael Dolch |
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On-Line Analysis of End-Expiratory AI in Mechanically Ventilated Patients using Ion-Molecular-Reaction Mass Spectrometry - Michael Dolch |
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A Comparison of the Volatiles from the Breath, Urine and Stool of Asymptomatic Male Humans Using 4D TOF GCMS - Norman Ratcliffe |
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Interference of CFC-Containing Inhalers with Measurements of Volatile Organic Compounds using Selected Ion Flow Tube Mass Spectrometry - Michael Epton |
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A Preliminary Study of Oral and Lung Breath in Patients with Oral Malodour using Selected Ion Flow Tube Mass Spectrometry - Brian Ross |
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Ion Mobility Spectrometry for Metabolic Profiling of Human Breath - Jörg Ingo Baumbach |
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Posters: Breath Condensates and Sensor Arrays |
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Breath Analysis: Relationship between Expiratory Parameters and Ethanol Consumption - Fukuoka Yu |
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Volatile Components in Exhaled Breath Condensate Compared with On-Line Breath Analysis Using SIFT-MS - Patrik Spanel |
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Exhaled Breath Condensate
Chair: Benjamin Gaston |
| 3:45 pm |
Clinical Applications of EBC Testing - John Hunt |
| 4:10 pm |
EBC in Children: Present Knowledge and Future Perspectives - Silvia Carraro |
| 4:30 pm |
Differentiation of Origin of Markers in Exhaled Breath Condensate
by Fractionated Sampling - Gunther Becher |
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Electronic Nose and Sensor Arrays
Chairs: Alan Gelperin, C. William Hanson, Erica Thaler |
| 4:45 pm |
Nanotube-Based Sensor Arrays for Clinical Breath Analysis - Alan Gelperin |
| 5:15 pm |
E-Nose, E-Ear, E-Eye: Imaging with Chemical Sensors for Disease Diagnosis and Treatment - Joseph Stetter |
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Selected Abstract Presentations (non-CME)
Technical and Clinical Aspects of Sensor Arrays |
| 5:45 pm |
Chemical Microsensor Arrays for Trace Analytes in Complex Gas Mixtures - Kurt Benkstein |
| 5:55 pm |
Diagnosis of Sinusitis using a Colorimetric Electronic Nose - Erica Thaler |
| 6:05 pm |
A Longitudinal Study of Healthy Individuals to Assess the Variation in the Simple Breath Gases Hydrogen, Hydrogen Sulphide, Ammonia, Ethanol and Carbon Monoxide - Ben de Lacy Costello |
| 6:15 pm |
The Characteristics of Novel Low Cost Sensors for Volatile Biomarker Detection - Norman Ratcliffe |
| 6:25 pm |
Recognition of Biofilm-Forming versus Non-Biofilm-Forming Bacteria using Electronic Nose - Dan Huang |
| 6:35 pm |
Closing Remarks - Raed A. Dweik and Gary Hunter |
| 6:50 pm |
Adjourn |
| 7:00 pm |
Reception and Poster Session
Chairs: Marco Freek, Daniel Laskowski, Metin Aytekin |
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| FRIDAY, NOVEMBER 2 |
| 7:00 am |
Registration, Continental Breakfast & Exhibits
MBNA Conference Center, 3rd Floor |
| 8:00 am |
Standardization Issues: Sampling, Quantification, Background Subtraction, and Standards
Chair: Terence Risby |
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Standardization Issues: Sampling, Quantification, Background Corrrection, and Units
Terence Risby |
| 8:30 am |
Panel Discussion: Standardization Issues
Moderator: Terence Risby
Panel: Nandor Marczin, Jochen Schubert, Joachim Pleil |
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Selected Abstract Presentations (non-CME) |
| 8:50 am |
Online-Monitoring of Lipid-Peroxidation Markers in Exhaled Breath by Mass Spectrometry - Michael Dolch |
| 9:00 am |
Implementation of Fowler's Method for Alveolar Air Sampling - Fabio Di Francesco |
| 9:10 am |
Variability Issues in Determining Concentration of Isoprene in Human Breath by PTR-MS - Svorad Stolc Jr. |
| 9:20 am |
Comparison of the Levels of some Breath Gases Originating Systemically and in the Mouth And Airways - Tianshu Wang |
| 9:30 pm |
Detection of Monobromamine, Monochloramine, and Dichloramine using selected Ion Flow Tube - Mass Spectrometry (SIFT-MS) - Michael Epton |
| 9:40 am |
Refreshment Break, Exhibits, Posters |
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Poster Session |
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Measurement of Volatile Organic Compounds in Expiratory Air Generated during Electrocautery - Michael Dolch |
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Real-Time Monitoring of Propofol in Expiratory Air in Children during Total Intravenous Anesthesia - Michael Dolch |
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Real-Time Monitoring of Propofol in Expiratory Air using Ion-Molecular-Reaction Mass Spectrometry - Michael Dolch |
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Fractionated Collection of Exhaled Breath and; Analysis of Exhalable Metabolites by Using IMS - Gunther Becher |
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Different Ion Mobility Spectrometers as Detectors of Breath Volatiles - Veronika Ruzsanyi |
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Reproducible Measurement of Acetone in Breath using Selected Ion Flow Tube-Mass Spectrometry - Michael Epton |
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Environmental Considerations
Chairs: Joachim Pleil |
| 10:00 am |
Role of Exhaled Breath Biomarkers in Environmental Health Science - Joachim Pleil |
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Selected Abstract Presentations (non-CME) |
| 10:30 am |
Quantitation of 1,3-Butadiene Kinetics using Exhaled Breath Concentrations as a Biomarker of Exposure - David Kim |
| 10:45 am |
Measurements of Air Pollutant Biomarkers with Exhaled Breath Techniques - Michael Madden |
| 11:00 am |
ecent Developments in Human Biomonitoring: Non-Invasive Assessment of Target Tissue Dose and Effects of Pneumotoxic Metals (Review) - Antonio Mutti |
| 11:15 am |
Exhaled Nitric Oxide as Noninvasive Marker of Airway Inflammation in Occupational Settings - Massimo Corradi |
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Mass Spectrometry and Benchtop Instrumentation II
Clinical Application of Mass Spectrometry Technologies
Chair: Hideo Ueda
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| 11:30 am |
Overview of Mass Spectrometry and Clinical Applications - Hideo Ueda |
| 12:00 pm |
Absolute Levels of some Trace Metabolites in Human Breath and their Distributions - David Smith |
| 12:30 pm |
Lunch, Exhibits, Posters |
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Clinical Application of Mass Spectrometry Technologies
Chair: Hideo Ueda
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Selected Oral Presentations |
| 1:30 pm |
A Breath Test to Determine Total Body Water from Deuterium Dilution: Does It Add Value in the Assessment of Fluid Status in Haemodialysis Patients? - Simon Davies |
| 1:40 pm |
Analysis of the Breath of Children with Cystic Fibrosis and Asthma - Beth Enderby |
| 1:50 pm |
13C/12C-Stable Isotope Breath Tests -The Different and Successful Concept of Breath Testing! - Guenter Wagner |
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Selected Topics in Clinical Breath Testing
Lung Cancer screening: Can breath analysis meet the Challenge?
Chairs: Peter Mazzone, Anton Amann, Raed A. Dweik |
| 2:00 pm |
Overview of Screening for Lung Cancer and the Role of Breath Analysis - Peter Mazzone |
| 2:30 pm |
Detection of Lung Cancer by Analysis of Exhaled Breath - Anton Amann |
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Breath Testing in the Critically Ill: Achievements and Challenges
Chairs: Jochen Schubert, Nandor Marczin |
| 3:00 pm |
Crescendo or Diminuendo for Exhaled Breath Monitoring of Acute Lung Injury?:
From Exhaled Nitric Oxide to Gas Phase Metabolomics - Nandor Marczin |
| 3:30 pm |
Refreshment Break, Exhibits, Posters |
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Poster Session |
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Early Lung Cancer Detection using Ion Mobility Spectrometry Data of Human Breath - Jörg Ingo Baumbach |
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Detection of 2-Pentylfuran in the Breath of Patients with Chronic Lung Disease Who Have Been Colonised or Infected with Aspergillus Fumigatus - Mona Syhre |
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Breathhydrogen Gas for Monitoring Movement of Intestinal Gas in Patients with Small-Bowel Pseudo-Obstruction - Yoshihisa Urita |
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Delayed Appearance of Ethanol and Acetaldehyde in the Skin Gas after Alcohol Ingestion - Akito Shimouchi |
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Release of Volatile Organic Compounds (VOCS) from the Lung Cancer Cellline A549 in Vitro: Possible Use as Tumor Markers - Anton Amann |
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Measurement of Acetone and Isoprene in Exhaled Breath and its Significance - Hideo Ueda |
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Selected Abstract Presentations (non-CME)
Chair: Anton Amann |
| 4:00 pm |
Faecalvolatile Organic Compounds in the Diagnosis of Necrotising Enterocolitis - Katy Garner |
| 4:15 pm |
Analysis of Volatile Organic Compounds in Exhaled Breath from Liver Disease Patients - Tanzeela Khalid |
| 4:30 pm |
Minimally Invasive Cardiac Output Measurment using Carboxyhemoglobin Densitometry by Breath Analysis - Makoto Sawano |
| 4:45 pm |
Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS) Measurement of Breath Ammonia Reduction Ratio (ARR) Measures Dialysis Efficacy - Jenny Scotter |
| 5:00 pm |
Volatile Analyses of the Headspace of Urine for the Diagnosis of Disease in Humans - Steve Smith |
| 5:15 pm |
Changes in the Mass Spectrums of Breath and Skin Gas during Exercise - Akito Shimouchi |
| 5:30 pm |
Gastric Air Bubble may Reflect Functional Disorder of Lower Esophageal Sphincter - Yoshihisa Urita |
| 5:45 pm |
Closing Remarks - Raed A. Dweik and Gary Hunter |
| 6:00 pm |
Reception of the Austrian Federal Ministry of Economy |
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| SATURDAY, NOVEMBER 3 |
| 7:00 am |
Continental Breakfast & Exhibits
MBNA Conference Center, 3rd Floor |
|
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New and Cutting Edge Sensor Technologies
Moderator: Gary Hunter |
| 8:00 am |
Overview - Gary Hunter |
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Selected Abstract Presentations (non-CME) |
| 8:30 am |
Online Measurement of Acetone in Expiratory Air by Mass Spectrometry during Cardiac Surgery - Michael Dolch |
| 8:45 am |
PTR-MS Analysis of Microbial VOCS for the Detection of Pathogens - Michael Bunge |
| 9:00 am |
Novel Microfabricated Sensors for Real-Time Breath Analysis - Cristina Davis |
| 9:15 am |
Breath Biomarker for Infectious Disease Measured using a Laser Based Sensor - Chad Roller |
| 9:30 am |
Development of a Compact Optical Sensor for Real-Time, Breath-by-Breath Detection of Oxygen - Conor Burke |
| 9:45 am |
Chemical Sensors based on Nanowires of Discotic Molecules - Yael Zilberman |
| 10:00 am |
Refreshment Break & Exhibits |
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Selected Topics: Society and Applications
Chairs: Anton Amann, Raed A. Dweik, Gary Hunter |
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Selected Abstract Presentations (non-CME |
| 10:20 am |
Breath Tests in Personalized Medicine: A Comprehensive Overview - Anil Modak |
| 10:35 am |
Relationship between Expiratory Gases and Obesity in a Japanese Population - Yamai Kiyonori |
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Relationship between Expiratory Carbon Monoxide and Irritable Bowel Syndrome Species in a Japanese Population - Yamai Kiyonori |
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Relationship between Expiratory Carbon Monoxide and Diabetes Mellitus in a Japanese Population - Yamai Kiyonori |
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Relationship between Expiratory Gases and Habitual Physical Activity in a Japanese Population - Yamai Kiyonori |
| 10:55 am |
What is Needed to Take an Innovation into Clinical Practice? - Mats Carlson |
| 11:10 am |
A Portable Unit for Metabolic Analysis (PUMA) - Daniel Dietrich |
| 11:25 am |
Breath Analysis of Tuberculosis with Differential Mobility Spectrometry - Jose Trevejo |
| 11:40 am |
Panel Discussion: Future Directions
Moderators: Gary Hunter, Raed Dweik and Anton Amann
Panel: Serpil C. Erzurum, Benjamin Gaston, Alan Gelperin, Gary Hunter, Nandor Marczin, Joachim Pleil, Terence Risby, Jochen Schubert, David Smith, Patrik Spanel, Hideo Ueda |
| 12:15 pm |
Closing Remarks |
| 12:30 pm |
Adjourn |
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