Table 4:
Guidelines for Surveillance of Colorectal Cancer (CRCa) and polyps
Moderate Risk
Recommendation
Interval

1 small (< 1 cm) tubular adenoma and no family history of CRCa

Colonoscopy

5 yrs after polyp removal; if normal, resume average-risk screening
> 2, or > 1 cm adenoma, or adenomas that are villous or have high grade dysplasia, or adenoma patients with a family history of CRCa

Colonoscopy

3 yrs after polyp removal; if normal, repeat every 5 yrs
Personal history of CRCa

Colonoscopy

3 yrs after surgery; if normal, repeat every 5 yrs
CRCa in FDR age < 60, or 2 or more FDR any age with CRCa Colonoscopy Every 3-5 yrs beginning age 40, or 10 yrs younger than the youngest cancer in FDR, whichever is earlier
High Risk
Recommendation
Interval

Family history of FAP

Refer to specialty center for genetic counseling and consideration of genetic counseling

At time of diagnosis
Sigmoidoscopy or colonoscopy Every 1-2 yrs beginning at puberty
Family history of HNPCC

Refer to specialty center for genetic counseling and consideration of genetic testing

At time of diagnosis

Colonoscopy

Every 2 yrs beginning at age 21-25 until age 40, then annually
Inflammatory bowel disease Colonoscopy with biopsy for dysplasia 8 years after the start of pancolitis/12-15 yrs after the start of L-sided colitis
FDR = first-degree relatives; FAP = familial adenomatous polyposis; HNPCC = hereditary nonpolyposis colorectal cancer
Copyright 2002 The Cleveland Clinic Foundation

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